We develop model systems to better understand: i) how reactions proceed at chemically modified thin films and electrodes; ii) the gradients of abiotic and signaling molecules that form across tissue- and tumor-like structures direct invasion, promote drug resistance, and regulates enzyme expression.
While these problems require techniques found in analytical chemistry, biochemistry, molecular biology, bioengineering, and surface science we are particularly interested in the technologies that allow us to quantitatively measure reactions and analytes.
The Latest News...
Welcome new graduate students! If you are interested in the group I encourage you to talk with members of the lab, and attend our group meetings! Group meetings are Wednesdays 8:30 - 10:30 am in Caudill 338 (starting Aug 30th).
Matt presented the group's work on 3D cell cultures at a symposium entitled Quantifying the Tumor Microenvironment at the ACS National meeting in DC. The symposium featured the work of Sean Burrows (Oregon State), Ashley Ross (U. Cincinnati), Shuang (Jake) Yang (FDA), and James Rusling (U. Conn).
Congratulations to Catherine, who received an RTNN Student Outreach Award!
Matt B's paper on a 3D colon tumor model, in collaboration with the Hummon lab at Notre Dame, is accepted at the Analyst!
Chad and Matt B's protocol on 3D invasion assays is published in Current Protocols in Chemical Biology!