Research Interests and Pursuits
The chemical underpinnings of the complex phenomena occurring in biological systems and at the interface of chemically modified electrodes require model systems whose microenvironment can be exquisitely controlled. The insights gained from these models are only as good as the measurements we can make, requiring the adaptation of current techniques (or the generation of new ones) to acquire accurate values with system-relevant resolution, selectivity, sensitivity.
Our intellectual pursuits are not driven by a single measurement technique but rather by questions and curiosities. These pursuits require team members to think deeply and broadly about science in a holistic manner, integrating concepts from disciplines that expand beyond chemistry to include biomedical engineering, cellular and molecular biology, materials and surface science, and toxicology.
The chemical underpinnings of the complex phenomena occurring in biological systems and at the interface of chemically modified electrodes require model systems whose microenvironment can be exquisitely controlled. The insights gained from these models are only as good as the measurements we can make, requiring the adaptation of current techniques (or the generation of new ones) to acquire accurate values with system-relevant resolution, selectivity, sensitivity.
Our intellectual pursuits are not driven by a single measurement technique but rather by questions and curiosities. These pursuits require team members to think deeply and broadly about science in a holistic manner, integrating concepts from disciplines that expand beyond chemistry to include biomedical engineering, cellular and molecular biology, materials and surface science, and toxicology.
Bioanalysis
We generate 3D tissue-like structures to quantify the cellular micro-environment effects on hormone signaling, drug responses and resistance, and molecular-level responses to potential toxins. Cellular processes are regulated by their micro-environment, particularly spatial and temporal changes in abiotic factors such as oxygen and pH and signaling molecules secreted by neighboring cells. These studies require new tools, culture devices, and sensors. |
Surface Analysis
The chemical composition of a surface dictates many of its physical and chemical properties, in particular its reactivity. We develop new attachment chemistries and surface patterning techniques to impart desired functionalities. In particular, we evaluate how surface chemistry dictates electron transfer rates, catalytic activity, and the durability of covalently attached electroactive molecules. |
Core Values and Expectations
We value the creativity that comes from a laboratory environment where everyone's ideas are welcomed and valued. We believe the best way to develop the out-of-the-box approaches needed to solve complex scientific problems is to value each individual while promoting the importance of the team.
We have a zero tolerance policy against oppression of any kind, including but not limited to sexism, racism, homophobia, transphobia, ableism and xenophobia. Everyone is welcome and celebrated in this safe space, where each of us works to support and promote each other. Each of us works to acknowledge and educate ourselves and others on unconscious biases, missteps, and misspeaks.
We value the creativity that comes from a laboratory environment where everyone's ideas are welcomed and valued. We believe the best way to develop the out-of-the-box approaches needed to solve complex scientific problems is to value each individual while promoting the importance of the team.
We have a zero tolerance policy against oppression of any kind, including but not limited to sexism, racism, homophobia, transphobia, ableism and xenophobia. Everyone is welcome and celebrated in this safe space, where each of us works to support and promote each other. Each of us works to acknowledge and educate ourselves and others on unconscious biases, missteps, and misspeaks.
The Latest News
11.2023
Welcome Jose and Ryan to the lab! New and exciting science is on the way.
Congratulations to Alexis H. on successfully completing your qualifying exam!
10.2023
Congratulations to Anna who was selected at the recipient of the 2023 Tanya R. Ellison Scholarship!
Taylor and Anna both presented posters at SERMACS in Durham!
09.2023
Check out our latest work on co-cultures in ACS Measurement Science Au. Congrats to Zack, Abel, Sarina, Z, and Nate!
Check out this great write-up on Taylor's PhD research on water splitting with silicon nanowire suspension reactors!
11.2023
Welcome Jose and Ryan to the lab! New and exciting science is on the way.
Congratulations to Alexis H. on successfully completing your qualifying exam!
10.2023
Congratulations to Anna who was selected at the recipient of the 2023 Tanya R. Ellison Scholarship!
Taylor and Anna both presented posters at SERMACS in Durham!
09.2023
Check out our latest work on co-cultures in ACS Measurement Science Au. Congrats to Zack, Abel, Sarina, Z, and Nate!
Check out this great write-up on Taylor's PhD research on water splitting with silicon nanowire suspension reactors!