WELCOME TO THE
|
|
We are accepting 2023 - 2024 rotation students. Please contact Matt if you are interested!
RESEARCH INTERESTS AND PURSUITS
The chemical underpinnings of the complex phenomena occurring in biological systems and at the interface of chemically modified electrodes require model systems whose microenvironment can be exquisitely controlled. The insights gained from these models are only as good as the measurements we can make, requiring the adaptation of current techniques (or the generation of new ones) to acquire accurate values with system-relevant resolution, selectivity, sensitivity.
Our intellectual pursuits are not driven by a single measurement technique but rather by questions and curiosities. These pursuits require team members to think deeply and broadly about science in a holistic manner, integrating concepts from disciplines that expand beyond chemistry to include biomedical engineering, cellular and molecular biology, materials and surface science, and toxicology.
Our intellectual pursuits are not driven by a single measurement technique but rather by questions and curiosities. These pursuits require team members to think deeply and broadly about science in a holistic manner, integrating concepts from disciplines that expand beyond chemistry to include biomedical engineering, cellular and molecular biology, materials and surface science, and toxicology.
|
BIOANALYSIS
We generate 3D tissue-like structures to quantify the cellular micro-environment effects on hormone signaling, drug responses and resistance, and molecular-level responses to potential toxins.
Cellular processes are regulated by their micro-environment, particularly spatial and temporal changes in abiotic factors such as oxygen and pH and signaling molecules secreted by neighboring cells. These studies require new tools, culture devices, and sensors. |
SURFACE ANALYSIS
The chemical composition of a surface dictates many of its physical and chemical properties, in particular its reactivity.
We develop new attachment chemistries and surface patterning techniques to impart desired functionalities. In particular, we evaluate how surface chemistry dictates electron transfer rates, catalytic activity, and the durability of covalently attached electroactive molecules. |
Core Values and Expectations
We value the creativity that comes from a laboratory environment where everyone's ideas are welcomed and valued. We believe the best way to develop the out-of-the-box approaches needed to solve complex scientific problems is to value each individual while promoting the importance of the team.
We have a zero tolerance policy against oppression of any kind, including but not limited to sexism, racism, homophobia, transphobia, ableism and xenophobia. Everyone is welcome and celebrated in this safe space, where each of us works to support and promote each other. Each of us works to acknowledge and educate ourselves and others on unconscious biases, missteps, and misspeaks.
We have a zero tolerance policy against oppression of any kind, including but not limited to sexism, racism, homophobia, transphobia, ableism and xenophobia. Everyone is welcome and celebrated in this safe space, where each of us works to support and promote each other. Each of us works to acknowledge and educate ourselves and others on unconscious biases, missteps, and misspeaks.
THE LATEST NEWS
05.2023
Welcome Jose! Jose is doing a summer (zero-year) rotation in the lab.
04.2023
Congrats to Dr. Zack Sitte and Dr. Tyler Larson on their successful PhD defenses!!
Congrats to Anna on receiving a Summer Undergraduate Research Award!
Congrats to Elizabeth on a successful honors thesis defense! Her thesis was entitled Investigation of how the tumor microenvironment mediates therapeutic resistance in breast cancer with new 3D cell culture methods.
Check out our newest paper in the Analyst. Congrats to Zack, Tyler, and former lab members Julie and Melanie!
Welcome Jose! Jose is doing a summer (zero-year) rotation in the lab.
04.2023
Congrats to Dr. Zack Sitte and Dr. Tyler Larson on their successful PhD defenses!!
Congrats to Anna on receiving a Summer Undergraduate Research Award!
Congrats to Elizabeth on a successful honors thesis defense! Her thesis was entitled Investigation of how the tumor microenvironment mediates therapeutic resistance in breast cancer with new 3D cell culture methods.
Check out our newest paper in the Analyst. Congrats to Zack, Tyler, and former lab members Julie and Melanie!